Optical Micro Imaging Technologies for Assessing Tissue Histology in vivo
时间🥦：2013年11月19日（周二）上午9点
地点：校图文信息中心2楼第2会议室
报告人：Dr. Xingde Li
主办单位：杏运官网平台
欢迎全校👭、全院师生参加👉！
Abstract:
Recent years have witnessed rapid development of high-resolution biophotonics imaging technologies. This seminar will report our recent efforts on developments of those technologies, including optical coherence tomography (OCT) and ultracompact fiber-optic multiphoton endomicroscopy platform. These technologies have shown significant potential to be translated to clinical use for imaging tissue microanatomies in vivo at a resolution approaching or even at that of standard histopathology but without the need for tissue removal. Thus they can function as a form of noninvasive “optical biopsy”, aiming to address unmet clinical needs in early disease detection, guidance of surgical intervention, and monitoring of treatment outcome. The physics principles, engineering challenges and solutions will be discussed, including the development of advanced lasers, MEMS technology, fiber optics, and ultracompact, high-performance imaging optics. Representative applications of these high-resolution technologies will be presented, including pre-cancer detection, airway physiology assessment, preterm birth risk assessment, and intra-operative guidance for neurosurgery. Other potential applications towards basic research such as functional neuroimaging on awake or freely walking animals will also be discussed.
Biography
Dr. Xingde Li received his BS degree in Physics from the University of Science and Technology of China (USTC) in 1990, and a PhD degree in Physics and Astronomy from the University of Pennsylvania in 1998. He is currently a full professor at the Department of Biomedical Engineering, Johns Hopkins University. He has pioneered several innovative biophotonics imaging probes/devices to enable translational applications of high-resolution optical micro imaging, such as OCT imaging needle, 3D volumetric balloon imaging technology, and ultracompact scanning fiber-optic multiphoton endomicroscopy etc.. He has received several awards including The Teacher of the Year Award (BioE at UW), the National Science Foundation Faculty Early Career Award, the International Association of Dental Research Innovation in Oral Care Award, and the Hartwell Foundation Individual Biomedical Research Award. He has been chairing many conferences such as the recent OSA Biomedical Optics Topical Meetings 2012 and Photonics Asia 2012 etc.. He currently serves on the editorial board of several international journals in the area of biomedical photonics including the Journal of Biomedical Optics (SPIE), Biomedical Optics Express (OSA), the IEEE Transactions on Biomedical Engineering, Light: Science and Applications (Nature Publishing Group and CIOMP) etc.. He has published about 80 peer-reviewed journal papers, with a total citation >8,400 and an H-index~39 (according to Google Scholar). He has served on grant review panels for many USA and foreign funding agencies, and is currently a charter member of the National Institutes of Health (NIH, USA) study section on Biomedical Imaging Technologies. He is a Fellow of the Optical Society of America (OSA), the International Society for Optics and Photonics (SPIE), and the American Institute for Medical and Biological Engineering (AIMBE).